Abstract
therapy (pancytopenia), but after omission the patient settled into the original condition. 28 patients of the 32 achieved remission after the second infusion of cyclophosphamide. Conclusion: Remission was maintained in all patients for 9 months on he average (mostly by CD patients) and the drug was well tolerated. Our experience suggest that intravenous pulse cyclophosphamide therapy may be a safe and effective treatment for patients with severe IBD unresponsive for conventional treatment, but further controlled study should be considered in the future in more diverse patient population.
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