P092: Antibiotic usage and appropriateness for a university hospital in Turkey: point prevalence results

Abstract

Objective: This study aims to determine antibiotic usage rates, causes of antibiotic usage and inappropriate usage rates in a university hospital with a 1200-bed capacity. Results: Of 666 patients staying in the hospital on the day of study, 262 (39.7%) were on antibiotics. Of those, 145 (55.3%) were on surgical wards, 98 (37.4%) were on medical wards and 19 (7.3%) were on paediatric wards. Of those 262 patients, 157 (59.9%) were taking only one type of antibiotic, 79 (30.2%) were taking two and 26 (9.9%) were taking three or more types of antibiotic. Antibiotic usage was appropriate in 55.7% (146 patients) and inappropriate in 44.3% (116 patients). The inappropriate antibiotic usage rate was 75.9% (88 patients) among patients on surgical wards. The most common cause of inappropriate usage was unnecessarily long prophylaxis time (68.2%, 60 patients). Inappropriate antibiotic usage was found in 24 (24.5%) patients out of 98 patients on medical wards. When the causes of antibiotic usage were analysed, it was found that the cause of antibiotic usage was infection in 36.2% (95 patients), prophylactic in 35.9% (94 patients), and empirical in 27.9% (73 patients). On the day the study was conducted, 367 antimicrobial drug were prescribed to 262 patients. The drugs most commonly prescribed were antibiotics from the cephalosporin (n=99, 27.0%) and fluoroquinolone (n=74, 20.2%) groups. When the diagnosis of 95 patients who were on antibiotics due to infection was reviewed, the most common infections were respiratory tract infections (n=36, 37.9%), urinary system infections (n=12, 12.6%), upper respiratory tract infections (n=8, 8.4%), bloodstream infections (n=6, 6.3%) and prosthesis infections (n=6, 6.3%).