P09.11.A INDICATIONS AND OUTCOMES OF NERVE RECONSTRUCTIONS AFTER RESECTION OF EXTREMITY TUMORS: A SYSTEMATIC REVIEW

Abstract

Abstract AIMS Peripheral nerve injuries resulting from tumor resection are unusual, but occasionally unavoidable. It can result in serious morbidity in motor deficits, sensory deficits, and even chronic pain. Nerve reconstruction after tumor resection is possible but rarely performed and outcomes are unclear. This study creates an overview of the indications and outcomes for nerve reconstructions after tumor resections. METHODS A systematic review was performed in March 2022 in PubMed and Embase according to the PRISMA guidelines. Search terms related to “tumor” and “nerve reconstruction” were used. Studies evaluating nerve reconstructions (nerve graft, transfer or coaptation) after tumor resection in extremities were included. A qualitative synthesis was performed on all studies. Patients with accurate description of their functional abilities were assigned to minimum grade on the MRC-scale. RESULTS Fifty-nine articles were included for quality synthesis after full text screening. A total of 84 patients were described of which 40 after resection of malignant tumors. Most patients improved in motor and sensory function after nerve reconstruction. In patients with benign tumors, 79% demonstrated functional recovery on the Medical Research Council (MRC) scale of ≥3, while 77% of patients with malignant tumors showed the same level of recovery. Most patients, 85%, recovered to a protective sensation of S2 or higher. CONCLUSION Nerve reconstruction after tumor resection can help recover both sensory and motor function. It should be considered in tumor surgery with chance of resection or damage to a nerve.