P0717 / #1448: IMMUNOMEDIATED ENCEPHALITIS IN PEDIATRICS, CASE REPORT

Abstract

Aims & Objectives: Immunomediated encephalitis, is a type of encephalitis given by antibodies against N-Methyl aspartate (NMDA). It occurs frequently in children under 18 years with predominance in females, and a good response to treatment. Methods: Male adolescent of 13 years of age referred to the psychiatric hospital for conduct disorder, aggressiveness and irritability, does not know his relatives, sensory disorder, alteration of the state of consciousness, disconnection with the environment, dyslalia, dysarthria, with personal pathological history of Sindrome from Steven Jhonson at 2 years old. Mother says that 3 days prior to admission presents abruptly behavioral disorders, does not obey orders, irritability, incongruity when speaking, clothes are placed upside down, also remains decayed, hyporexic, argues that adolescent is calling attention however the picture is exacerbated by what he decides to be valued by a doctor, denies trauma, refers to thermal quantification not quantified in the last 3 days. Results: The following results are reported in the tests performed on our patient: • Simple brain CT scan: normal • Simple and contrasted brain resonance imaging: normal • cerebral fluid: normal • • Negative drug panel • normal eye fundus • Anti NMDA in spinal fluid, serum and serum: positive Our patient later required tracheostomy and gastrostomy, as well as physical, language and occupational therapy. however, the connection with the medium was not recovered, nor the prostrationConclusions: Among the most frequent clinical characteristics, the presentation of fever with psychiatric abnormalities, abnormal movements and orofacial dyskinesias stands out; the latter occur more frequently in the pediatric patient