P0615 / #1213: EVALUATION OF THE VASOACTIVE-INOTROPIC SCORE IN PATIENTS WITH SEPTIC SHOCK IN A PICU

Abstract

Aims & Objectives: Vasoactive-inotropic Score (VIS) correlation with severity of illness is well established for post-cardiac surgery patients, but it is still controversial for patients with septic shock. We aimed to evaluate its correlation with mortality of these patients Methods: Retrospective study in a university hospital in Porto Alegre-RS, Brazil, approved by the institutional ethics committee. We reviewed electronic health records of patients admitted from january/2016 to june/2018 to the PICU with diagnosis of septic shock and calculated VIS as proposed by Gaies et al in 2010, considering the maximum score in 48 hours Results: 181 patients admissions were included, with median age of 1,3 y/o (IQR 0,3-5,2) and a mortality rate of 28,7% (53). The median VIS for survivors and non-survivors were 16,7 (IQR 11,0-33,3) and 40,3 (IQR 17,2-99,3), respectively (p < 0,001). The AUC to evaluate VIS prediction of mortality was 0,687. Considering 25 as a threshold for the VIS, the OR for mortality was 3,7 (CI 1,8-7,3) Conclusions: The VIS maximum in 48 hours correlates with severity of illness in patients with septic shock and shows a good predictive capability of mortality in these patients.