P06.05: Correlation of preoperative endometrial sampling with pathology in symptomatic and asymptomatic patients with known endometrial polyps

Abstract

To determine the accuracy of preoperative endometrial biopsy sampling results in patients with pathologically proven endometrial polyps. 123 pre-, peri-, and post-menopausal patients underwent operative hysteroscopy and dilatation and curettage for endometrial polyps over a calendar year period (2002). Medical records were reviewed for evidence of office endometrial sampling as part of the workup for peri- or post-menopausal bleeding, or incidentally found endometrial polyps by TVS. All patients had at least one TVS evaluation for possible polyps and all had pathologic confirmation of endometrial polyps at pathology. 66 patients were pre- or peri-menopausal and 57 were post-menopausal. Of the 66 pre/peri-menopausal patients, 58 of 66 (88%) were symptomatic and 12% asymptomatic. Of the 57 postmenopausal patients, 43 of 57 (75%) were symptomatic and 25% asymptomatic. Thirty four endometrial biopsies were performed in total: 10 in the pre/peri-menopausal group and 24 in the post-menopausal group. Of the biopsies performed, 0 of 10 were suspicious for polyp in the pre/peri-menopausal group, and 4 of 24 (16%) in the post-menopausal group. Only 12% of the total endometrial biopsy specimens obtained suspected endometrial polyps in this group studied. Preoperative endometrial biopsy sampling appears to not be helpful in the preoperative workup in symptomatic and asymptomatic patients when endometrial polyps are suspected, especially in the pre- and peri- menopausal patients.