Abstract
Background and objective Repetitive transcranial magnetic stimulation is a promising tool to study and modulate brain plasticity and connectivity. The aim of this study was to investigate the effects of theta burst stimulation (TBS) on the Stroop task (ST) performance and related changes in resting state functional brain connectivity. dorsal attentional resting state network. Patients and methods Twenty healthy young subjects received a session of stimulation of the right inferior frontal gyrus (IFG) and the left superior parietal lobule (SPL) using continuous TBS (cTBS) or intermittent TBS (iTBS) protocol in a randomized order. Prior to and right after each stimulation session each participant performed an fMRI version of the ST and resting state fMRI measurement in 3T Siemens Prisma. Behavioural results from the ST and functional connectivity analyses of the resting state data were performed. Results We observed a trend towards increased speed of some ST subtests after the iTBS of the SPL. This stimulation induced a significant increase in connectivity between the SPL and the nodule of the cerebellum as well as increased connectivity within the dorsal attentional network. Conclusion Our results reveal that using TBS we may modify cognitive speed and intranetwork connectivity within the dorsal attentional network.
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