Abstract
Purpose To evaluate foot perfusion in patients with critical limb ischemia (CLI) using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and estimate perfusion parameters changes after percutaneous transluminal angioplasty (PTA). Methods Eight patients (5 male, median age 68 years, range 58–79 years) with CLI [Rutherford 4 (n = 2), Rutherford 5 (n = 5), Rutherford 6 (n = 1)] were examined. All patients underwent DCE-MRI of the lower calf and foot, 1 day before (pre-PTA) and 1 month after (post-PTA) revascularization. Perfusion parameters such as blood flow (BF), Ktrans, Kep were analyzed and applied for statistical comparisons. Wilcoxon signed rank tests were used to compare pre and post-PTA perfusion parameters. Results Revascularization was technically successful in all cases with significant clinical improvement. In addition, the ankle brachial index (ABI) increased from 0.35 ± 0.2 to 0.76 ± 0.25, p Conclusions DCE-MRI may be a useful means for the diagnosis of foot hypo-perfusion. It seems also to be a promising tool for evaluation of PTA outcome, as significant restitution of perfusion parameters was observed after successful revascularization.
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