P033: Incidence estimate of Clostridium difficile infection in Emilia-Romagna Region by linkage of administrative and laboratory data

Abstract

Methods We linked regional data of PHDF and labs by anonymous patient code and we considered only public hospitals with at least 1 identified positive lab test for CD. CDI was defined as follows: “Confirmed case” (Cc) where a specific ICD9 code (00845) was present on the PHDF or an unspecific code for diarrhoea (or intestinal infection) and positivity for CD toxin was retrieved from the lab; “Probable case” (Pc) where either a specific ICD9 code without positivity for CD toxin test or exclusively CD toxin positivity was present. We considered only people older than 1 year and incidence was calculated both for all inpatients and for residents in ER. By linking dates of hospital admission and discharge and date of lab testing we defined CDI as hospital-acquired (HA: >2 days from admission within 28 day from discharge), community-acquired (CA: within 2 days from admission and after 84 days from possible previous discharge, or none admission) or indeterminate (IA: all the remaining cases with hospitalization and lab test).