Abstract
P03-02. SCID-hu mice generate HIV specific human immune responses after gp96 vaccination
Highlights
Open AccessSCID-hu mice generate HIV specific human immune responses after gp vaccination
NOD.SCID common gamma chain (NSG) knockout mice have no functional adaptive immune system of their own and readily accept human CD34+ hematopoietic stem cell xenografts (SCID-hu)
We have previously developed a cell based vaccine system utilizing a secreted form of heat shock protein gp96 along with HIV gag protein (293-gp96Ig-HIVgag)
Summary
SCID-hu mice generate HIV specific human immune responses after gp vaccination. Address: Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA * Corresponding author from AIDS Vaccine 2009 Paris, France. Published: 22 October 2009 Retrovirology 2009, 6(Suppl 3):P19 doi:10.1186/1742-4690-6-S3-P19. AIDS Vaccine 2009 Anna Laura Ross Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1471-2105-10-S12-info.pdf
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