Abstract

The third-generation Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitor (TKI) osimertinib is well-tolerated and can improve disease-free survival (DFS) for EGFR mutant stage IB-IIIA completely resected non-small cell lung cancer (NSCLC) patients. However, limited data on osimertinib as neoadjuvant therapy for resectable, EGFR-mutant NSCLC exists. This multicenter, retrospective study aimed to investigate the efficacy and safety of osimertinib as neoadjuvant therapy in resectable patients with stage IA-IIIB NSCLC.

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