Abstract
Pediatric chronic nonbacterial osteomyelitis (CNO) is a sterile inflammatory bone disorder of presumed autoimmune or autoinflammatory etiology. Sometimes CNO associated with other rheumatologic conditions, such spondyloarthritis, sacroileitis, IBD, pyoderma gangrenosum and psoriasis as well as a part of distinct autoinflammatory disease (AID), such as DIRA syndrome.
Highlights
Pediatric chronic nonbacterial osteomyelitis (CNO) is a sterile inflammatory bone disorder of presumed autoimmune or autoinflammatory etiology
Sometimes CNO associated with other rheumatologic conditions, such spondyloarthritis, sacroileitis, IBD, pyoderma gangrenosum and psoriasis as well as a part of distinct autoinflammatory disease (AID), such as DIRA syndrome
The onset of disease was in the age of 10 months with small bone lesion in distal epiphysis of femur and intensive irritability
Summary
P03-006 - Pamidronate rapidly decreases CRP and TNFΑ in CNO Introduction Pediatric chronic nonbacterial osteomyelitis (CNO) is a sterile inflammatory bone disorder of presumed autoimmune or autoinflammatory etiology. Sometimes CNO associated with other rheumatologic conditions, such spondyloarthritis, sacroileitis, IBD, pyoderma gangrenosum and psoriasis as well as a part of distinct autoinflammatory disease (AID), such as DIRA syndrome. Case report 14 year old girl was admitted to our department with pain, low and moderate grade fever, delay to thrive and history of osteomyelitis.
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