P022: Antibiograms of consecutive urinary tract samples in elderly

Abstract

Results Following organisms were predominantly isolated (N first samples/N second samples): E. coli (7188/1654), E. faecalis (1282/403), P. mirabilis (1230/313), K. pneumonia (673/ 173), P. aeruginosa (293/120), E. aerogenes (375/203), S. aureus (158/54), M. morganii (347/89), Group B streptococci (149/31), C. freundii complex (101/29). When comparing first versus second samples antibiograms for E. coli, a decrease in susceptibility was found for the following antimicrobial agents: cotrimoxazole -6.9%; nitrofurantoin -2.8%, fosfomycin 0.0%; ciprofloxacin -10.8%; cefuroxime -5.6%; amoxicillin-clavulanic acid -5.6%; ampicillin -10.5%. For E. faecalis, marked decreases were found for nitrofurantoin -2.4%; fosfomycin -2.2%; -ciprofloxacin -10.3%; and only mild decreases for amoxicillin-clavulanic acid 0.0%; and ampicillin -1.2%. For K. pneumoniae decreases were in the range of -2.9 to -4.1% for cotrimoxazole, ciprofloxacine, cefuroxime and amoxicillin-clavulanic acid, and was -12.4% for nitrofurantoin. For S. aureus and C. freundii no decrease (<-0.1%) was seen for nitrofurantoin and fosfomycin. For E. aerogenes, decreases of -18 and -12.5% were found for cotrimoxazole and fosfomycin, respectively. M. morganii showed in consecutive samples less susceptibility for cotrimoxazole (-16.2%), fosfomycine (-13.0%) and ciprofloxacin (-10.5%), while only a marginal decrease was found for nitrofurantoin (-0.5%).