P02-385 - Childhood trauma experience and obsessive-compulsive disorder in Chinese population: A case control study

Abstract

BackgroundChildhood trauma is known to predispose to a variety of psychiatric disorders, including anxiety, mood, and substance use. However, the relationship between childhood trauma and obsessive-compulsive disorder (OCD) has not been well studied. The aim of the present study is to compare childhood trauma experience between OCD and controls, and explore its impact on symptoms of OCD.MethodsOne hundred eighty-five outpatients who met DSM-IV diagnosis of OCD and 132 gender- age- matched controls were included in this study. The Early Trauma Inventory Self Report-Short Form (ETISR-SF) was administered to all participants to evaluate 4 types (general, physical, emotional and sexual) of trauma and its severity. The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) was used to measure the severity of symptoms of OCD patients.ResultsOCD patients showed a significantly greater severity in all four types of trauma when compare with controls. 77% of OCD patients reported at least one type of childhood trauma experience, and 18% reported sexual trauma. Sexual trauma experience is significantly associated with obsessive but not compulsive symptoms of OCD patients. When compared to female OCD patients, male patients reported significantly higher scores on general trauma, physical abuse and emotional abuse; but lower of sexual abuse.ConclusionThe present study revealed the high prevalence of childhood trauma among OCD patients, which is consistent with evidence from previous studies suggesting that childhood trauma may play a role in the development of mental disorders. It may be important to consider the impact of childhood trauma in OCD clinical management.