Abstract

Purpose The primary aim is to compare the change in serum 25OHD concentration between three forms of supplemental vitamin D3: a lipid-emulsified form administered in a sesame oil base, a non-emulsified chewable tablet, and a non-emulsified form administered to 25-hydroxycholecalciferol (25-OHD) insufficient <33ng/ml (75 nmol/ml) patients. The secondary aim is to compare the proportion of participants reaching an “optimal” 25-OHD concentration ≥33ng/ml (75 nmol/ml) between Vitamin D supplement groups following supplementation.

Highlights

  • The primary aim is to compare the change in serum 25OHD concentration between three forms of supplemental vitamin D3: a lipid-emulsified form administered in a sesame oil base, a non-emulsified chewable tablet, and a non-emulsified form administered to 25-hydroxycholecalciferol (25-OHD) insufficient

  • The secondary aim is to compare the proportion of participants reaching an “optimal” 25-OHD concentration ≥33ng/ml (75 nmol/ml) between Vitamin D supplement groups following supplementation

  • This three-arm, randomized clinical trial compared the difference in serum 25-OHD concentration between the three arms at baseline and after random administration of one of the three vitamin D preparations for 12-weeks at a dosage of 10,000 IU Vitamin D per day (N=60 vitamin D insufficient subjects and N=30 sufficient controls)

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Summary

Open Access

A comparative effectiveness trial of high-quality vitamin D3 nutritional supplements to replete serum vitamin D. From International Research Congress on Integrative Medicine and Health 2012 Portland, Oregon, USA. Purpose The primary aim is to compare the change in serum 25OHD concentration between three forms of supplemental vitamin D3: a lipid-emulsified form administered in a sesame oil base, a non-emulsified chewable tablet, and a non-emulsified form administered to 25-hydroxycholecalciferol (25-OHD) insufficient

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