P0195 : Development of a smartphone application to enable remote monitoring in the outpatient management of cirrhotic ascites

Abstract

9.3±7.5 ng/ml with a range of 0.9 to 46.1 ng/ml. 25(OH)D3 levels differed significantly between Child Pugh scores and showed a negative correlation with the model of end stage liver disease (MELD) score. Patients with decompensated liver disease had significantly lowered 25(OH)D3 levels. 25(OH)D3 levels significantly differed between patients with infectious complications compared to those with none and individuals with SBP (spontaneous bacterial peritonitis) had significantly lower 25(OH)D3 levels compared to patients without SBP. 25(OH)D3 levels ≤6ng/ml as well as serum 25(OH)D3 concentrations ≤10ng/ml levels were associated with higher mortality compared to higher 25(OH)D3 levels (HR 1.82 for 6ng/ml and HR 1.71 for 10ng/ml, respectively). In a multivariate Cox regression model 25(OH)D3 levels were independently associated with shorter OS. Conclusions: 25(OH)D3 deficiency is associated with advanced liver disease and low 25(OH)D3 levels are an indicator for a poor outcome and are associated with infectious complications.