Abstract
Background This study investigated the effects of Tai Chi Chuan on biological markers and psychological factors of patients diagnosed with advanced invasive ductal carcinoma. Methods 105 breast cancer patients, aged 32–42 years, and 50 healthy female participants, aged 26–36 years, were recruited for this study. Patients underwent a mastectomy for invasive ductal carcinoma, and completed four cycles of FEC (500 mg/m2 fluorouracil, 75 mg/m2 epirubicin, and 500 mg/m2 cyclophosphamide) chemotherapy. Peripheral blood was drawn from participants to analyse biological markers such as white blood cell (WBC) and red blood cell (RBC) count and cytokine levels (IL-2, IL4, IL6, IFN-γ and TNF-α). Following treatment, the patients participated in a TCC program for 12 months and biomarkers in patients were measured. A psychological factor-based questionnaire was also conducted. Findings After 12 months of TCC, the levels of cytokines of patients and healthy groups showed no statistically significant differences. The total WBC count was 7.55 ± 1.25 (versus 8.04 ± 1.05 in the healthy group, p Interpretation TCC exercise can be used as a physical and mental treatment for the rehabilitation of post-treatment breast cancer patients for psychological and biological improvements.
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