Abstract
Background Triple-negative breast cancer (TNBC) has been demonstrated to carry poor prognosis, but whether or not there exists any age-related variation in TNBC outcomes has yet to be elucidated. The current population-based study investigated the early survival pattern of elderly women with TNBC and identified outcome-correlated factors. Methods We searched the Surveillance, Epidemiology, and End Results (SEER) database and enrolled female primary non-metastatic TNBC cases. The patients were subdivided into elderly (⩾70 years) and young groups ( Findings 9908 female TNBC patients diagnosed from 2010 to 2011 were included in the current study (20.4% elderly). Elderly patients exhibited distinctly worse overall (log-rank p Interpretation Elderly patients with TNBC displayed higher early mortality within the first 2 years of diagnosis compared with younger individuals. The observed lower rate of loco-regional treatment might be associated with worse outcome for these patients.
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