P0130 Quality of life in patients with colorectal carcinomatosis peritonei after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Abstract

<h3>Background</h3> An increasing number of patients with colorectal cancer are presenting with peritoneal carcinomatosis and more centres are performing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). While morbidity and mortality are shown to be acceptable after surgery, quality of life should be assessed. <h3>Methods</h3> 21 patients who had CRS and HIPEC from 2001 to 2012 for colorectal peritoneal carcinomatosis and who were still alive at follow up were included. The EORTC QLQ-CR29 was administered to the patients. Scores at baseline and at 6months and 12months after CRS and HIPEC were summarised by median and interquartile range, and changes were tested using the Wilcoxon matched-pairs signed-rank test. <h3>Findings</h3> After a median follow-up of 12months, there was no statistical difference in scores when comparing by age, sex, recurrence, PCI score, and presence of complications. There was no significant change in most scores, but body image score improved at 6months, while sexual interest scores and urinary frequency scores worsened at 6 and 12months, respectively. <h3>Interpretation</h3> Our study shows that colorectal peritoneal carcinomatosis patients can achieve a good quality of life after CRS and HIPEC, with improvement in body image scores.