Abstract
Materials and methods Sixty-seven males (42%) and 92 females (58%), aged between 5 to 18 years, suffering from headache, were divided into three diagnostic categories, according to the ICHD-III classification: migraine with aura (MWA), migraine without aura (MWoA) and tension-type headache (TTH). Serum vitamin D level lower than 20 ng/ml was considered pathological. Immunohistochemical methods of chemiluminescence were used to determine blood 25(OH)D level.
Highlights
Statistical significance between serum 25(OH)D levels and headache in the pediatric population is still controversial
A difference resulted in the limits of statistical significance (p = 0.07) in 25(OH)D serum level in children with migraine without aura (MWoA) compared to patients with migraine with aura (MWA) and THH
Hypovitaminosis D was found in 56% of the children with MWoA, in 50% of patients with MWA and in 44.4% with tension-type headache (TTH)
Summary
Statistical significance between serum 25(OH)D levels and headache in the pediatric population is still controversial. A supplementary vitamin D therapy in children with headache allowed us to note an improvement in the clinical symptoms in terms of frequency and severity [1]. Children with BMI>90°C (p = 0.47), and serum concentration was not lower in adolescents and pre-adolescent than children under 10 years. A difference resulted in the limits of statistical significance (p = 0.07) in 25(OH)D serum level in children with MWoA compared to patients with MWA and THH. Aim To study vitamin D blood levels in primary headaches and to show the relationship with clinical parameters influencing clinical course of the headache
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