Abstract

To evaluate complications after genetic amniocentesis. Retrospective analysis of 1153 women who underwent genetic amniocentesis from 1999 to 2005, which was done by ultrasound-guided insertion of a 22-gauge needle. The mean maternal age was 37 ± 4 years. 1148 (99%) women were in singleton pregnancy, 4 (0.03%) in twin pregnancy and one (0.08%) in triplet pregnancy. Amniocentesis was performed between 12 and 32 weeks' gestation (mean 14 ± 1 weeks). The most common indication for amniocentesis was maternal age over 35 year —988 (86%). 17 (1.4%) patients had pregnancy loss after amniocentesis: 7 (0.6%) women had missed abortion and 10 (0.8%) had amniotic fluid leakage. 1 (0.1%) had pain in hypogastrium after the procedure, but she delivered at term. In 8 (0.7%) cases the cell culture of amniotic fluid was unsuccessful and procedure was repeated. The pregnancy loss rate in women who underwent genetic amniocentesis was 1.4%.

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