Abstract
Central-line associated blood stream infection (CLABSIs)is associated with increase hospital costs and length of stay. Antibiotic lock therapy (ALT) along with systemic antibiotics appears to be an option for catheter salvage. Most studies on ALT have focused on Coagulase-negative staphylococcal (CoNS) infections. However, CLABSIs due to extended spectrum β- lactamase (ESBL)-producing Gram-negative bacteria (GNB) is more common in our setting.
Highlights
Central-line associated blood stream infection (CLABSIs) is associated with increase hospital costs and length of stay
Antibiotic lock therapy (ALT) along with systemic antibiotics appears to be an option for catheter salvage
Most studies on ALT have focused on Coagulase-negative staphylococcal (CoNS) infections
Summary
Central-line associated blood stream infection (CLABSIs) is associated with increase hospital costs and length of stay. Antibiotic lock therapy (ALT) along with systemic antibiotics appears to be an option for catheter salvage. Most studies on ALT have focused on Coagulase-negative staphylococcal (CoNS) infections. CLABSIs due to extended spectrum b- lactamase (ESBL)-producing Gram-negative bacteria (GNB) is more common in our setting
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