P006 - Association between trigeminal neuralgia and multiple sclerosis: A population-based study

Abstract

Background Multiple sclerosis (MS) is a chronic neuro-inflammatory disease of central nervous system (CNS) which is characterized by variable evolution and different clinical manifestations. Although pain is one of the most common problems of MS patients, the presence of trigeminal neuralgia (TN) in a patient's life-span is rare. Methods In a retrospective study, we investigated the presence of TN amongst MS patients inspecting total Isfahan multiple sclerosis (TIMs) records which were registered in Isfahan Multiple Sclerosis Society (IMMS) from April 2003 until July 2014. Results We could find 20 cases with diagnosis of both TN and MS, suggesting a significant higher prevalence of TN among MS patients (0.4%) in comparison with general population (0.04%) (P?0.05). Conclusions Our results showed a significant association between these two disorders supporting previous hypothesis based on the role of MS in etiology of TN. Multiple sclerosis (MS) is a chronic neuro-inflammatory disease of central nervous system (CNS) which is characterized by variable evolution and different clinical manifestations. Although pain is one of the most common problems of MS patients, the presence of trigeminal neuralgia (TN) in a patient's life-span is rare. In a retrospective study, we investigated the presence of TN amongst MS patients inspecting total Isfahan multiple sclerosis (TIMs) records which were registered in Isfahan Multiple Sclerosis Society (IMMS) from April 2003 until July 2014. We could find 20 cases with diagnosis of both TN and MS, suggesting a significant higher prevalence of TN among MS patients (0.4%) in comparison with general population (0.04%) (P?0.05). Our results showed a significant association between these two disorders supporting previous hypothesis based on the role of MS in etiology of TN.