P0022 Clinicopathological features of gastric cancer: A single-centre experience

Abstract

Background Gastric carcinoma remains a common disease worldwide with a dismal prognosis. This investigation was undertaken to define the demographic, clinicopathological, and treatment modalities in patients with gastric adenocarcinoma. Methods We did a retrospective study of 56 patients with primary gastric cancer admitted to the King Abdullah Medical City in the Holy Capital, a tertiary care hospital in Saudi Arabia, from January 2011 to December 2012, with follow-up until December 2013. Findings The mean age of patients at diagnosis was 60.3 years (range 26–94 years), and 62.2% were male. The male-to-female ratio of patients was 1.6:1.88.8% of patients were Saudis and 11.2% were non-Saudi (three were Yamani and one was Pakistani). None had a family history of gastric cancer. 82.2% presented with stages III and IV disease. Histological types of adenocarcinoma lesions were intestinal in 46.7% of patients, diffuse in 33.3%, and mixed in 20%. Helicobacter pylori infection was documented in 20% of patients. The most common complaint was abdominal pain (88.9%). 71.1% of patients died within the first year and only 11% of them lived for more than 2 years. Interpretation Gastric cancer is the second most common gastrointestinal malignancy after colorectal cancer in King Abdullah Medical City. Most of our patients presented with advanced-stage cancer, which reflects its poor prognosis. This fact will need to be confirmed by a longer period of observation and an adequate sample size.