Abstract
Lymphoma of the central nervous system[1] accounts for 2% of cerebral tumors; it is typically located in the supratentorial and periventricular white matter; extra-axial localization is rare. When found in the cerebellopontine angle or the Meckel cave[2], the differential diagnosis includes meningioma, trigeminal neurinoma or epidermoid carcinoma. Correlated painful symptoms are often atypical, mimicking trigeminal neuralgia, cluster headache or trigeminal autonomic cephalgias (TACs). Recommended therapy involves: chemotherapy with cyclophosphamide, high dose cytarabine, steroid (dexamethasone), etoposide, and rituximab (CHASER) followed by whole-brain irradiation. We describe the case of a young man who came to our observation for excruciating headache related to mediastinal lymphoma with bilateral infiltration of the the ganglion of Gasser.
Highlights
We describe the case of a young man who came to our observation for excruciating headache related to mediastinal lymphoma with bilateral infiltration of the the ganglion of Gasser
Written informed consent to publication was obtained from the patient(s)
Case report A 30-year-old man came to our attention suffering for the past 3 months of left fronto-orbital-zygomatic headache with intense pain, mainly nocturnal, subcontinuous, initially with nasal congestion and conjunctival injection, unresponsive to FANS, triptans and oxygen therapy
Summary
Lymphoma of the central nervous system [1] accounts for 2% of cerebral tumors; it is typically located in the supratentorial and periventricular white matter; extraaxial localization is rare. We describe the case of a young man who came to our observation for excruciating headache related to mediastinal lymphoma with bilateral infiltration of the the ganglion of Gasser. Associated with thickening of the dural surface and adjacent the temporal pole, suggesting granulomatous or lymphoproliferative disease.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
