P-EP016. Cortical involvement of post stroke epilepsy in children: A systematic review

Abstract

Introduction. Epilepsy as an incident after stroke may cause disability in children. This very detrimental effect makes particular marker for knowing the tendency to develop epilepsy after stroke at later time very crucial. The aim of this study is to explain cortical involvement in post stroke epilepsy incident in children. Methods. The researcher searched in the Medline and Cochrane Library electronic databases (2000–2020) to identify observational studies of post stroke epilepsy in children. The inclusion criteria for the selected studies were accessible in full-text, English language, <19 year-old children with post stroke epilepsy, additional assessments and adequate follow-up. The researcher checked the validity of the studies with Critical Appraisal Skills Programme (CSAP) checklist on cohort studies. Results. A total of 7 retrospective cohort studies which involved 603 children were included. The incidences of epilepsy after stroke were varied. Early onset strokes have higher tendency to cause post stroke epilepsy. The features of cortical involvement were found radiologically (CT scan and MRI) in 6 studies, and one study using Electroencephalography (EEG). Cortical involvement has been reported in post stroke epilepsy. It was reported to have the highest percentage in early seizure after stroke. Conclusion. Cortical involvement is an important marker of determining the prognosis of stroke in children, regarding the incidence of subsequent epilepsy.