P-88 A multicenter analysis of the correlation between overall survival and progression-free survival and the number of chemotherapeutic key drugs used in patients with advanced/unresectable pancreatic cancer: Results from the NAPOLEON study

T Shirakawa,Y Ueda,M Shimokawa,F Koga,J Nakazawa,A Komori,S Arima,M Fukahori,A Makiyama,H Taguchi,T Honda,S Uneda,M Yoshida,T Shibuki,K Nio,Y Ide,N Ureshino,K Mitsugi,T Otsuka

doi:10.1016/j.annonc.2020.04.170

P-88 A multicenter analysis of the correlation between overall survival and progression-free survival and the number of chemotherapeutic key drugs used in patients with advanced/unresectable pancreatic cancer: Results from the NAPOLEON study

T Shirakawa, Y Ueda + Show 17 more

Open Access

https://doi.org/10.1016/j.annonc.2020.04.170

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Journal: Annals of oncology : official journal of the European Society for Medical Oncology	Publication Date: Jul 1, 2020
License type: publisher-specific-oa

Affiliation: Japan Medical Association, Japanese Red Cross Kumamoto Hospital, National Hospital Organization Kyushu Cancer Center, Saga-Ken Medical Centre Koseikan, Kagoshima City Hospital, Oita University, Kagoshima University, Kurume University, Japan Community Healthcare Organization, Kyushu Hospital, Sendai Shakai Hoken Hospital, Nagasaki University, National Cancer Center Hospital East, Sasebo City General Hospital, Takamatsu Red Cross Hospital

#Unresectable Pancreatic Cancer #Overall Survival + Show 8 more

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Abstract

The appearance of FOLFIRINOX (FFX) and gemcitabine plus nab-PTX (GnP) prolonged the overall survival (OS) of advanced or unresectable pancreatic cancer (AUPC) dramatically. However, the correlation between progression-free survival (PFS) and OS with the two regimens for AUPC cases as first-line chemotherapy (CTx) has been unknown. Also, we have no established data about the correlation between the number of chemotherapeutic key drugs used for AUPC and its OS despite their increase. We, therefore, performed a retrospective study to validate the two correlations in the real world.

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