P-761 - Depression is a hidden complicating factor in diabetic women with obesity

Abstract

Introduction According to WHO reports, the risk of chronic noncommunicable diseases increases with raised body mass index and females have both obesity and depression rates higher. Aims To analyze the association obesity-psychiatric disorders in patients with diabetes and modified BMI, by gender. Methods We assessed emotional (HADS,PHQ,MADRS,HAM-A), cognitive (MMSE, clock test), and medical status in 50 consecutively admitted patients (March-June 2011), in our medical ward. Results Sex ratio F/M:35 / 15; the mean duration of diabetes was lower in women: 9 vs. 15 years; at least two of diabetes complications have been noted in similar proportions, 62% vs. 66%; obesity / overweight ratio women =3:1/ men = 1:1; men being treated mostly with OAD (73.3% vs. 42.8%). Stressful life events, in the past year, have been reported mostly in men (60% vs. 40%).Anxiety (F/M - 22.8% / 20%), insomnia (F/M - 68% / 60%), and an average score of 27 in MMSE were similarly present in both sexes. Depression was strikingly more common in females (clinical depression F/M: 40% / 26.6%, subclinical depression F/M: 22.8% / 13.3%). Conclusions Untreated clinical and subclinical symptoms of depression in women with diabetes and modified body mass index is a rule, and the aspect appears to be chronic. In men unspecific anxious-depressive symptoms and insomnia could be a reaction to a stressful life event.The results raise the suspicion that depression is a hidden complicating factor in diabetic women with obesity. In this group, early specific psychiatric and psychological interventions may improve the multidisciplinary treatment team approach.