Abstract
Hyperprolactinaemia causes hypogonadotropic hypogonadism. Hyperprolactinaemia could be pre-existing in some patients with schizophrenia. Dopamine is the most important prolactin inhibiting factor, while dopaminergic hyperactivity has been implicated to the pathophysiology of psychosis. We present the case of a patient with hypogonadism secondary to chronic, untreated hyperprolactinaemia who developed acute psychotic symptoms. Psychotic symptoms resolved soon after treatment with aripiprazole in conjunction with cabergoline, with a concomitant decrease in serum prolactin levels. An interesting cause effect relationship of hyperprolactinaemia and psychosis has been suggested
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