Abstract
Testicular cancer is the most common solid-organ tumor found in men aged 15-35 years. While cancer treatment is succesful in most of these cases, fertility status in these individuals has recently become a main focus. Sperm nuclear DNA structural organization is essential for proper sperm function, including post-fertilization events. It is not clear if the cancer is capable of inducing changes in the genomic integrity of the spermatozoa. The objective of this study was to compare DNA fragmentation in patients with testicular cancer and men with normal sperm analysis.
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