Abstract
Luteal defect is common during IVF cycles using GnRH agonist (GnRH-a), indicating that common mechanisms might be supraphysiological steroid serum concentrations routinely observed in stimulation cycles adversely affecting LH secretion. Recent studies have demonstrated that steroidogenic acute regulatory protein (StAR) regulates the rate-limiting step in steroid hormone biosynthesis. The objective of the present study was to determine whether StAR expression differed in luteinized granulosa cells with different low dosage of GnRH-a in long-suppression GnRH-a protocol in IVF.
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