P-40 A correlation between BCL-2 modifying factor, p53 and livin gene expressions in cancer colon patients

Abstract

Accumulating evidence has revealed that livin gene and BCL-2 modifying factor (BMF) gene are closely associated with the initiation and progression of colon carcinoma by activating or suppressing multiple malignant processes. These genes that can detect colon cancer are a promising approach for cancer screening and diagnosis. This study aimed to evaluate the correlation between livin, BMF and p53 genes expression in colon cancer tissues of patients included in the study, and their relationship with clinicopathological features and survival outcome in those patients.