Abstract
In Costa Rica gastric adenocarcinoma is the second leading cause of cancer-related death. The development of this malignancy is a complex multistep process involving numerous genetic alterations. Gastric cancer development proceeds through three different molecular pathways: the chromosomal instability (CIN) pathway, the mutator phenotype (or microsatellite instability pathway, MSI) pathway and the CpG island methylator phenotype (CIMP) pathway. The mutator phenotype pathway is characterized by frequent mutations in regions of the DNA containing microsatellite sequences.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
