Abstract
Patients with intermediate-stage hepatocellular carcinoma (HCC) are treated with locoregional therapy such as transarterial chemoembolization (TACE) because curative therapy is not always an option and there is no standard systemic therapy. TACE therapy achieves tumor responses, but progression and recurrence are common and often occur within 1 year. Early evidence shows encouraging activity and durable clinical response for checkpoint inhibitors (CIs), such as durvalumab, as treatment for advanced HCC (Kelley, et al.
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