Abstract
One of the most common problems associated with lifestyle today is obesity. Obesity increases oxygen consumption because of increased mechanical load and myocardial metabolism. Thus, there is an increase in the formation of mitochondrial respiratory superoxide, hydroxyl radical and hydrogen peroxide. So, obesity sets the stage for many diseases and they activate cellular immunity, T-lymphocyte-stimulated monocytes/macrophages induces leads to neopterin secrete. In this study, it was aimed to determine the changes in neopterin levels of individuals with obese and to evaluate these changes in terms of oxidant balance and cellular immunity. This study included 22 obese patients and 20 healthy individuals. Serum NP levels were determined by using high performance liquid chromatography (HPLC). While the neopterin levels ranged from 2.73 to 6.84 μmol/l in the control group, those of obese were found to be between 5.41 to 11.64 μmol/l. In our study, the neopterin levels in obese were found statistically significantly higher than the control group data (p
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