P.2.b.054 Psychiatric induced disorders and quality of life of substance abusers with chronic hepatitis C under interferon-alpha treatment

Abstract

adherence was higher in A-B groups and it correlated with selfesteem improvement (r = 0.68) and self-esteem score (r = 0.72). Groups A, B and Groups C, D have benefited of similar psychotherapy forms, both showing as a result a slight decrease in HAM-D scores, when compared to control group (p< 0.1). The main difference between the 4 psychotherapy groups was related to the intensive emphasis on self-esteem and self-valorization in group A and B. Our study suggests that this self-esteem improvement may have a causal implication in treatment adherence increase. Discussions and Conclusions: An increased self-esteem is likely to assure a good treatment adherence independently of the depressivity scores. However, the study was conducted on mild and moderate depression with homogenous HAM-D scores. Treatment adherence seems to be related more to a subjective image of self rather than depression. Improving self-esteem was correlated to significant improvements in treatment adherence rates.