Abstract
impulsivity are central features of the symptomatology of ADHD. • The 5C-CPT measures vigilance in a way similar to the human CPT, and allows for the measurement of response disinhibition (false alarm rate), which is important when validating animal models of ADHD. • Selection of rats from a “normal” population that display poor performance in the 5C-CPT may provide a more translational animal model of ADHD. • AIM: To investigate the effects of psychostimulant and non-stimulant drugs on attention, impulsivity and performance in adult rats divided into high and low performers in the 5C-CPT.
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