Abstract
Background Potentials evoked by transcranial magnetic stimulation (TEP) differ depending on the cortical areas where TMS has been applied. Moreover, TEP underly a marked development during childhood and adolescence. Methods We examined motor cortex and prefrontal TEP (N100 component) in healthy children and children with attention deficit/hyperactivity disorder. Results Topographic differences between motor cortex and prefrontal TEP are presented. Difficulties in artifact correction (e.g. blinks) are discussed. A method of calculating focal lateralized potentials (similar to the lateralized readiness potential algorithm) is presented. Discussion/ significance TEPs are a valuable tool to examine also the excitability of non-motor cortex in children and adolescents. However, a proper control of artifactual sources in essential.
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