P-145 - Association between depersonalization and panic disorder in a sample of patients with anxiety disorders and mood

Abstract

Introduction There is a strong association between depersonalization (DP) and panic disorder (PD), as documented by Roth (1960) and later by Cassano (1989) 1 . In the PD is shown a prevalence of 7.8% to 82.6% from the DP. The aim of our study was to evaluate the association between depersonalization symptoms and PD in a sample of patients with anxiety disorders and mood. Method a sample of 310 patiens was assessed with: SCID-P for axis I diagnosis and SCI-DER (structured clinical interview for depersonalization and derealization symptoms, lifetime version) 2 . Results Through a linear regression analysis we underline that, the presence of depersonalization symptoms, irrespective of age, gender and mood disorder, is significantly associated with the PD diagnosis (total score SCI-DER Tot p=0.001; derealization p=0.001; somatopsychic depersonalization p=0.001; autopsychic depersonalization p=0.003; affective depersonalization p=0.047). Conclusion the presence of depersonalization symptoms must carefully assess in clinical setting and suggest the presence of panic disorder.