P-1192 - Results of effectiveness of long term using of neurocognitive trainings and atypical antipsychotics

Abstract

Neurocognitive deficits in schizophrenia patients is a major health and social problem of modern psychiatry nowadays. Many patients with schizophrenia are of working age and there is a high enough percentage of their disability. Objective To study the influence of neurocognitive training on higher cortical functions in schizophrenia patients and to evaluate their effectiveness in the treatment of schizophrenia. Material and methods All patients received adequate pharmacotherapy with atypical neuroleptics. Patients of the main group (102 patients) additionally participated in the training of cognitive deficits. Patients in the comparison group (48 patients) received only pharmacotherapy. Study design:The assessment of long term data means prospective follow-up study after 1-year trainings. Neurocognitive training is a psycho correctional training which aim is to improve the disabled cognitive functions such as memory, attention and executive functions. All patients took part in the prospective follow-up study. There was a good compliance as well as in group with trainings and in group without them. During the prospective follow-up study we observed data on compliance and number of re-hospitalizations. The analysis of follow-up study showed that, 1) Number of patients with drug compliance is higher in group with neurocognitive trainings 2) Number of patients with partial drug compliance is higher in comparison group 3) Number of patients who stopped taking medication was the same in both groups Conclusion The neurocognitive training showed itself as an effective method of correcting neurocognitive deficits. Inclusion trainings in the rehabilitation program helps to reduce the term of the patients stay in hospital.