Abstract

Carcinoembryonic antigen (CEA) is a complex glycoprotein produced by 90% of colorectal cancers (CRC). Preoperative CEA level is considered as a predictive factor of survival in CRC patients. However, the prognostic significance of elevated preoperative CEA that normalized after resection is unknown. We aim through this study to assess the role of variations of preoperative and postoperative CEA levels in predicting nonmetastatic CRC relapse.

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