P.104: Donor morbidity following living donor liver transplantation: A single small volume center experience.

Abstract

Background: Living donor liver transplantation (LDLT) has being increasingly performed to alleviate the shortage of cadaveric liver graft. The main disadvantage of this procedure is the risk of complications or even death in a healthy donor who does not derive any medical benefits from the operative procedure. We present the experience of donor morbidity following LDLT at Dong-A University Medical Center for five years. Methods: From Jan. 2014 to Mar. 2019, 53 LDLTs and 47 deceased donor LT were performed at our hospital. Donor demographics, graft type, complications, length of stay and overall survival were evaluated. Donor morbidity was assessed objectively using the modified Clavien-Dindo classification. Results: There were 48 cases of right lobe graft, 2 cases of left graft, 1 left lateral graft for pediatric patient and 2 cases of dual grafts (two left lobe). Median follow-up was 31.1 months. Mean donor age, donor BMI and hospital stay were 25.6 years, 21.5 kg/m2 and 11.4 days. There was no donor mortality. Grade II complications were observed in 2 (3.7%), Grade IIIa in 4 cases and IIIb in 1 case were developed in 5 (9.4%). All donor morbidities except Grade I complications was 7/53(13.2%). Conclusions: Although small cases, our experience shows that donor hepatectomy for living donor liver transplantation is a safe procedure in a small volume center. Our donor morbidity of 13.2% is comparable to most high-volume centers across the world. Meticulous preoperative evaluation, careful operation and proper remnant volume are guarantee for the safety of donors in LDLT.