P.062 MR Venography predicts increased intracranial hypertension in children with hydrocephalus

Abstract

Background: We investigated whether the presence of dural sinus narrowing is a more reliable marker of intracranial hypertension / shunt failure in children than the imaging finding of hydrocephalus. -Methods: Cranial MRIs of n=12 children were included when being well and when there was definitive intracranial hypertension as per follow-up and intraoperative results (gold standard). Images werde assessed for hydrocephalus on T2w images and narrowing of dural sinuses on MR vengraphy (diameter of <50%). Results: Dural sinuses narrowing was detected with a sensitivity of 0.67, a specificity of 1.0, PPV of 1.0 and NPV of 0.75 (Table 1). Hydrocephalus was detected with a sensitivity of 0.5, a specificity of 0.83, PPV of 0.75 and NPV of 0.63. Results differed between the test methods (p = 0.01, Cochrane Q test). Conclusions: Dural sinus narrowing more reliably predicted intracranial hypertension, a sign which might significantly improve care in critically ill children.Age at MRIShuntfailure as per clinical follow-up(Goldstandard)HydrocephalusDural Sinus NarrowingPatient #Years1 = yes2 = no1 = yes2 = no1 = yes2 = no111104000261116000312101120004181011900050110101060010011071710117000810111100009011110001081018000111410114000121810018000Shuntfailure(Goldstandard)AffectedNonaffectedtotalHydrocephalusPositive618Negative61016121224Shuntfailure(Goldstandard)AffectedNonaffectedtotalDural Sinus NarrowingPositive808Negative412161212