P.056 Predictability of pituitary tumor resection and recurrence following endoscopic endonasal trans-sphenoidal surgery

Abstract

Background: The surgical treatment of pituitary tumour has undergone substantial changes over time. In this study we evaluated our institutional results for pituitary tumour surgery using the endoscopic endonasal trans-sphenoidal (EETS) approach. Methods: Patient demographic, clinical and surgical data were extracted from medical records. Preoperative MRI images were reviewed. The SIPAP classification was applied to the pituitary tumors. Chi2 test and t test were used for statistical analysis. Results: 202 cases were identified. Functional tumors were present in 29% of the cohort. Patients with a suprasellar or parasellar SIPAP score of 0 or 1 had complete resection of their tumor in 66.6% of cases, compared to 29% with a suprasellar or parasellar SIPAP score ≥ 2 (Risk Ratio 2.3 CI 1.58-3.39, p=0.0005). When the tumor was completely resected radiologically, the mean time to recurrence was not different for the SIPAP 0 or 1 group which was 27 months in comparison to 34 months for the group with a SIPAP score 2 (p=0.13). Conclusions: Our study results showed that the preoperative MRI SIPAP score can be used to better inform patients about their expected outcomes of EETS.