P-02-17 Efficacy of Low-Intensity Extracorporeal Shockwaves Treatment in Erectile Dysfunction

Abstract

Evaluate efficacy of LISWT to improve erectile function in ED patients. 20 consecutive non-vascular mild ED patients (mean IIEF-15 EF domain = 19,4 ± 2.1); mean age 56.3 years, range 39-68) underwent 6 LISWT sessions, each session delivering 1500-4000 shocks. For 2 weeks before, during the treatment period and four weeks after LISWT patients were asked to refrain form PDE5i use. Once PDE5i treatment was re-introduced (Tadalafil 2.5 mg daily), patients were evaluated at 1, 2 and 6 months follow-up by using IIEF-15 erectile function domain and EHS questionnaires. Penile color-Doppler parameters in the flaccid state were evaluated before, during and after treatment according with standardized procedure. Collected data were analyzed using T-test and Wilcoxon test. No statistically significative difference in IIEF-15 EF domain, EHS and flow parameters was found when baseline and follow-up parameters were compared. EF-domain showed an improvement at both 2 and 6 months follow-up visit (mean 19.4 ± 2.1 vs 14.3 ± 1.3, p= 0.06) compared with baseline. Moreover, percentage of patients showing EF improvement increased during the treatment: 25 % at 6th treatment session vs 43.75 % at 2 months follow-up and 62.5 % at 6 months follow-up, respectively. Compared with baseline, EHS score improved in 7/20 patients at the end of the treatment session, in 8/16 patients at 1 months follow-up, and in 8/16 at 2 and 6 months follow-up (p < 0.05).