P-0186 - Relation of General Self-Efficacy with Stress, Symptoms and Quality of Life in Colorectal Cancer Patients

Abstract

Background: Symptoms related with colorectal cancer (cc), may increase the psychological and physical status and deteriorate patients quality of life. The purpose of this study was to evaluate symptoms, general self-efficacy, stress and quality of life of cc patients. In addition, our purpose was to investigate correlation between general self-efficacy and other parameters, at baseline and actual modification one year after adjuvant chemotherapy. Conclusions: One year after adjuvant chemotherapy, impairment was observed in all evaluated parameters. Change of general self-efficacy was mainly related to change of stress levels, moderate but equally important related to severity and intervention of symptoms in quality of life and at a minor extent to energy (subscale of LASA) of patients. The results of this study show that general self-efficacy, stress, physical symptoms and energy of patients are crucial factors for cc patients and therefore, physicians should consider these psychological and physical dimensions. Methods: 90 cc patients were included in our study. General self-efficacγ was evaluated with « General Perceived Self-Efficacy scale » (GSE), quality of life was measured with « Linear Analogue Scale Assessment» (LASA), stress was evaluated with the (HAD) scale, impairment and involvement of symptoms were measured with «MD Anderson Symptom Inventory» (MDASI) questionnaire, at the time of diagnosis and one year after adjuvant chemotherapy. Results: Measurements one year after adjuvant chemotherapy showed that general self-efficacy decreased (28.86 + /- 6.42), stress increased (9.56 + /- 4.42), quality of life impairment (6.74 + /- 1.81) following the severity of symptoms (3.24 + /- 2.62). Actual modification at the time of diagnosis and one year after adjuvant chemotherapy showed important negative correlation between general self-efficacy and stress (p < 0.0005). Moderate negative correlation was observed between general self-efficacy and symptoms (MDASI severity of symptoms: p = 0.003, intervention of symptoms: p = 0.002), while low positive correlation was found between self-efficacy and energy LASA scale (p = 0.048). Results: Measurements one year after adjuvant chemotherapy showed that general self-efficacy decreased (28.86 + /- 6.42), stress increased (9.56 + /- 4.42), quality of life impairment (6.74 + /- 1.81) following the severity of symptoms (3.24 + /- 2.62). Actual modification at the time of diagnosis and one year after adjuvant chemotherapy showed important negative correlation between general self-efficacy and stress (p < 0.0005). Moderate negative correlation was observed between general self-efficacy and symptoms (MDASI severity of symptoms: p = 0.003, intervention of symptoms: p = 0.002), while low positive correlation was found between self-efficacy and energy LASA scale (p = 0.048). Conclusion: One year after adjuvant chemotherapy, impairment was observed in all evaluated parameters. Change of general self-efficacy was mainly related to change of stress levels, moderate but equally important related to severity and intervention of symptoms in quality of life and at a minor extent to energy (subscale of LASA) of patients. The results of this study show that general self-efficacy, stress, physical symptoms and energy of patients are crucial factors for cc patients and therefore, physicians should consider these psychological and physical dimensions.