P-01-017 ED and peyronie disease, commonly seen in diabetic patients

Abstract

58 y/o male presents with progressive penile deviation and painful erection for the past eight months as well as decreased penile rigidity and difficulty with intercourse. Patient states normal desire with frequency of having one to two intercourse every week. He denies any abnormal ejaculatory functions with IELT around 5 minutes. On Psychosocial history he confesses having good relationship with a 52 y/o partner whom they have been married and lived together for over 20 years. He denies any past insulting factors. On past medical history he states having diabetes mellitus for the past 6 years which he has been watching his diet and taking Metformin and Glibenclamide. He denies any peripheral neuropathy. He denies any coronary artery diseases, hypertension, nor thyroid diseases. He has been smoking tobacco x 10yr (quit 20 years ago). no alcohol on Exam, testicles were normal size and shape. Penis was in normal size. We found a 2 x 0.5 cm Peyronie plaque to mid penis. Routine labs ordered. All came back normal except for elevated FBS and HbA1c and slightly elevated lipid. Patient was educated regarding pathophysiology of Peyronie Disease and possible treatment options. Lekoptin injection advised every other week as well as oral treatment of tadalafil 5 mg daily and Co-Q 10 100mg daily. Patient received 6 injections in 3-month period and reported significant improvement in his deviation and rigidity. Another course of 3-month injection advised to patient, however, patient declined further injection.