Abstract

Background: There is a pressing need to monitor the cognitive outcomes of patients undergoing deep brain stimulation (DBS) for movement disorders, despite the prevalence of pre-operative cognitive evaluations. Previous research has demonstrated the potential for DBS to induce reversible cognitive decline, highlighting the need for post-operative cognitive monitoring. Methods: To address this issue, the present study sought to improve upon the existing Autonomous Cognitive Examination through the development of a 5-minute web-based exam. This examination leverages the capacity of machine-learning algorithms to evaluate complex multimodal inputs, including cognitive and movement disorders, and is made available through a web-based platform for physicians to administer to their patients. Results: The outcome of this study was the development of a cognitive evaluation platform, which enables physicians to administer and view results of a brief cognitive examination with sensitivity to multiple domains of cognition, including movement disorders. The web-application based screening examination is easily accessible and can be used on any device. Conclusions: This web-based cognitive examination offers a crucial solution for monitoring longitudinal cognition in high-risk patient populations undergoing DBS for movement disorders. Its ability to assess complex multimodal inputs has broad applications beyond movement disorders and serves as a valuable tool for detecting cognitive decline.

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