Abstract
Peri-implant mucositis represents an inflammatory lesion of the mucosa surrounding an endosseous implant, without the loss of the supporting peri-implant bone. Considering its reversible nature, every effort should be made to contrast it, thus avoiding the eventual progression towards peri-implantitis. The aim of the present randomized clinical trial is to evaluate the efficacy of the ozonized water against peri-implant mucositis. A total of 26 patients diagnosed for this latter clinical condition were randomly divided according to the professional oral hygiene protocol performed on the pathological sites at baseline, at T1 (1 month), and T2 (2 months). Group 1 underwent an ozonized water administration (experimental treatment), whereas Group 2 underwent a pure water one (control treatment). Both administrations were performed with the same professional irrigator (Aquolab® professional water jet, Aquolab s.r.l. EB2C S.r.l., Milano, Italy) with no differences in color or taste between the two substances delivered. At each appointment, the following indexes were assessed: the Probing Pocket Depth (PPD), Plaque Index (PI), Bleeding on Probing (BoP), and Bleeding Score (BS). As regards intragroup differences, in Group 1 ozonized water significantly and progressively reduced all the clinical indexes tested, except for PI in the period T1–T2, whereas no significant differences occurred within the control group. Despite this, no significant intergroup differences were generally detected between the two treatments. Accordingly, the role of ozone for the management of peri-implant mucositis deserves to be further investigated.
Highlights
In recent years, the application of ozone in medicine and dentistry has increased because of its several recognized benefic actions
Focusing on the applicability of ozone in dentistry, several clinical conditions have been treated by recourse to ozone therapy, e.g., the management of wound-healing, dental caries, oral lichen planus, gingivitis and periodontitis, halitosis, osteonecrosis of the jaw, post-surgical pain, plaque and biofilms, root canal treatment, dentin hypersensitivity, temporomandibular joint disorders, and teeth whitening [7,8,9,10]
Probing Pocket Depth (PPD) was calculated in millimeters; Bleeding on Probing (BOP) and Plaque Index (PI) were calculated in percentages; Bleeding Score (BS) was calculated with the relative score
Summary
The application of ozone in medicine and dentistry has increased because of its several recognized benefic actions. Gingivitis is regarded as the result of a progress accumulation on the teeth of dental plaque/calculus, which is a complex bacterial biofilm embedded into a polymeric matrix. This causes an inflammatory condition which continues in cases where proper domiciliary and professional oral hygiene procedures are not performed to remove this biofilm. Despite this condition being reversible, it may evolve into an irreversible one (i.e., periodontitis) with the degradation of soft and hard tooth-supporting tissues and, eventually, tooth loss [15,16]
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