OZONE THERAPY IN THE TREATMENT OF OSTEONECROSIS OF THE JAW: A CASE REPORT

Thaís Santos Cerqueira,César Werneck Noce Dos Santos,Nathália De Almeida Freire,Erika Castro Kuzsminszky,Giulianna Lima Pinheiro,Isabela Simões Susini Ribeiro,Beatriz Da Rocha Miranda Venturi

doi:10.1016/j.oooo.2019.06.379

Abstract

Osteonecrosis of the jaw has been reported in several patients who have used or are using bisphosphonates by oral or intravenous route. The treatment of (ONJ) includes the administration of local and systemic antibiotics and surgical intervention. Ozone therapy is indicated to treat these injuries, promoting the repair of bone tissue, avoiding invasive procedures, and reducing the use of antibiotics, which is extremely important for elderly and compromised patients. A 74-year-old female patient on chemotherapy treatment with cetuximab for colorectal cancer returned after dental extraction of #38 with incomplete wound healing, pain on palpation, soft tissue depression, and mild bone exposure. In the following case report, we show the efficacy of a 21-day course of antibiotic and 2 weekly applications of ozone followed by a simple sequestrectomy with primary wound closure. In the 8-month follow-up of the patient the clinical aspect of the treated region was normal before the treatment. Osteonecrosis of the jaw has been reported in several patients who have used or are using bisphosphonates by oral or intravenous route. The treatment of (ONJ) includes the administration of local and systemic antibiotics and surgical intervention. Ozone therapy is indicated to treat these injuries, promoting the repair of bone tissue, avoiding invasive procedures, and reducing the use of antibiotics, which is extremely important for elderly and compromised patients. A 74-year-old female patient on chemotherapy treatment with cetuximab for colorectal cancer returned after dental extraction of #38 with incomplete wound healing, pain on palpation, soft tissue depression, and mild bone exposure. In the following case report, we show the efficacy of a 21-day course of antibiotic and 2 weekly applications of ozone followed by a simple sequestrectomy with primary wound closure. In the 8-month follow-up of the patient the clinical aspect of the treated region was normal before the treatment.

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